Cades Cove is an isolated valley located in the Tennessee section of the Great Smoky Mountains National Park. The valley was home to numerous settlers before the formation of the national park. Cades Cove, the single most popular destination for visitors to the park, attracts more than two million visitors annually because of its well preserved homesteads, sc…Cades Cove is an isolated valley located in the Tennessee section of the Great Smoky Mountains National Park. The valley was home to numerous settlers before the formation of the national park. Cades Cove, the single most popular destination for visitors to the park, attracts more than two million visitors annually because of its well preserved homesteads, scenic mountain views, and abundant display of wildlife. The Cades Cove Historic District is listed on the National Register of Historic Places.