Panama City Beach is a resort town in the Florida Panhandle, and principal city of the Panama City Metropolitan Area. It is a popular va…Panama City Beach is a resort town in the Florida Panhandle, and principal city of the Panama City Metropolitan Area. It is a popular vacation destination, especially among people in the Southern United States, and is located in the "Emerald Coast" area. Panama City Beach had a population of 18,094 at the 2020 census, up from 12,018 in 2010. Panama City Beach's slogan is "The World's Most Beautiful Beaches" due to the unique, sugar-white sandy beaches of the Florida Panhandle.