The San Francisco 49ers are dealing with some devastating early-season injuries to Deebo Samuel and Christian McCaffrey. It's ...

Whatever negativity existed from the 49ers’ Brandon Aiyuk and Trent Williams contract issues were nowhere in evidence Monday ...

• Third-and-8 from MIN 46: Yiadom is on the right side of the 49ers defense but follows a Vikings receiver in motion to the ...

All indications reportedly suggest the NFL is not investigating the San Francisco 49ers over their handling of running back Christian McCaffrey's ...

Rams 0-2. Series record: 49ers lead 78-69-3. Last meeting: Rams beat 49ers 21-20 in Santa Clara, Calif. on Jan. 7. Last week: 49ers lost to Minnesota 23-17; Rams lost to Arizona 41-10. 49ers offense: ...

His rivalry with the 49ers and lack of success against this team is a major national talking point. As for the home team, the ...

Thompson: Aiyuk. He’s a purer receiver who gets upfield. Aiyuk’s 17.9 yards per catch last season was a career high. Deebo ...

I n a strategic announcement that may influence their defensive lineup, the San Francisco 49ers have officially named veteran ...

Injuries are easily the worst part of fantasy football. Unfortunately, even ahead of Week 1, not everyone is healthy, ...

Jimmie Kaylor shares his Week 1 NFL DFS picks, sleepers, rankings, values and player pool for San Francisco 49ers vs. New ...

Despite Achilles concerns, Christian McCaffrey is primed to headline our Jets vs 49ers prop picks for Monday Night Football ...