San Francisco 49ers head coach Kyle Shanahan reveals how he’s approaching his division rivals without one of the best players ...

Minneapolis, Minnesota, USA; San Francisco 49ers tight end George Kittle (85) runs after the catch against the Minnesota ...

In Week 1, Juszczyk, the wife of San Francisco 49ers fullback Kyle Juszczyk, created one of her custom jackets but with a ...

San Francisco head coach Kyle Shanahan told reporters on Monday that star wide receiver Deebo Samuel will miss “a couple” of ...

NFL Draft 49ers Low Profile 59FIFTY Hat from New Era and everyone will know you are the coolest fan around. This San Francisco 49ers 2017 NFL Draft Cap features bold 49ers graphics on a classic fitted ...

Now comes the hard part for Kyle Shanahan — devising a game plan without Deebo Samuel and Christian McCaffrey.

The San Francisco 49ers saw the Los Angeles Rams' extensive list of injuries ahead of their Week 3 matchup and upped the ante. 49ers All-Pro tight end George Ki ...

San Francisco 49ers wide receiver Brandon Aiyuk will be the first guest to appear on his teammates' show Cleats and Convos ...

The last time these 49ers won a game in Minnesota was all the way back in 1992. To put that into perspective, Steve Young and ...

The San Francisco 49ers have Super Bowl aspirations, but they didn't look like a championship-caliber team in Sunday's 23-17 ...

The San Francisco 49ers were expecting to get strong safety Talanoa Hufanga back against the Los Angeles Rams in Week 3. Head ...