The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle reported soreness in his hamstring after Wednesday’s practice.
Rams 0-2. Series record: 49ers lead 78-69-3. Last meeting: Rams beat 49ers 21-20 in Santa Clara, Calif. on Jan. 7. Last week: 49ers lost to Minnesota 23-17; Rams lost to Arizona 41-10. 49ers offense: ...